Partial least squares-based gene expression analysis in preeclampsia
نویسندگان
چکیده
منابع مشابه
Partial least squares based gene expression analysis in renal failure
BACKGROUND Preventive and therapeutic options for renal failure are still limited. Gene expression profile analysis is powerful in the identification of biological differences between end stage renal failure patients and healthy controls. Previous studies mainly used variance/regression analysis without considering various biological, environmental factors. The purpose of this study is to inves...
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In this paper, we propose a nonparametric rank-based alternative to the least-squares independent component analysis algorithm developed. The basic idea is to estimate the squared-loss mutual information, which used as the objective function of the algorithm, based on its copula density version. Therefore, no marginal densities have to be estimated. We provide empirical evaluation of th...
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Distances matrices are traditionally analyzed with statistical methods that represent distances as maps such as Metric Multidimensional Scaling (MDS), Generalized Procrustes Analysis (GPA), Individual Differences Scaling (INDSCAL), and DISTATIS. MDS analyzes only one distance matrix at a time while GPA, INDSCAL and DISTATIS extract similarities between several distance matrices. However, none o...
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Post-transplant lymphoproliferative disorder (PTLD) is a common complication of therapeutic immunosuppression after organ transplantation. The majority of PTLD is of B-cell origin and over 90% of PTLDs are Epstein-Barr virus (EBV) positive (Paya et al., 1999; Gottschalk et al., 2005). Clinically, EBV negative patients tend to occur later and have an overall poorer prognosis(Nelson et al., 2000)...
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OBJECTIVE Posttraumatic stress disorder (PTSD) is an adverse psychological response to traumatic events. Microarray technology for large-scale gene expression analysis facilitates the identification of signatures that underlie the pathogenesis of PTSD. Previous studies mostly used variance/regression analysis without considering array specific factors. We aim to investigate the underlying mecha...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2015
ISSN: 1676-5680
DOI: 10.4238/2015.june.18.2